Abstract: ICT has had a profound impact on traditional manufacturing companies and leads to smart manufacturing ecosystem paradigm. The enterprise can deploy and implement in three dimensions including life cycle & value stream, manufacturing hierarchy, and physical system functions to transform into smart manufacturing paradigm. Smart manufacturing key enabling technologies generally cover nine technologies including industrial internet of things, cloud computing, big data, computer simulation, augmented reality, additive manufacturing, horizontal and vertical systems integration, autonomous robots and cybersecurity. This paper sorts out and summarizes these enabling technologies, and analyzes their latest applications in smart manufacturing domain.