Abstract: 2.5D glass has been used in mobile screen lenses. Due to the high hardness and brittleness of glass materials, precision grinding is needed. In this paper, a grinding tool for mobile phone lens with vacuum adsorption is designed, which can ensure the precise positioning of glass in high-speed processing. Then the grinding process of 2.5D glass is studied experimentally. The glass lenses obtained have no appearance defects and the dimension accuracy meets the requirement of graphic dimension tolerance.