Abstract: The nuclear grade Z2CN19-10N stainless steel plate was prepared by laser melting deposition technology. The microstructure of the deposited and heat-treated samples was analyzed by metallographic microscope and scanning electron microscope, and the tensile properties of the samples were tested at room temperature. The results show that the microstructure of Z2CN19-10N stainless steel deposited by laser melting is composed of columnar crystals that grow through multilayer epitaxial growth along the increase direction of deposition. The columnar crystals contain a number of elongated dendritic crystals arranged in neat order. A large number of ferrites arranged along the increase direction of deposition are distributed on the austenitic matrix. After solid solution treatment, ferritic elimination was involved, and a large number of carbides were precipitated on the austenite matrix. The deposited structure of Z2CN19-10N austenitic stainless steel has good tensile properties at room temperature, tensile strength up to 539 MPa, yield strength up to 264 MPa, elongation up to 54%, reaching the forging level.