Abstract: Aiming at the problems of the poor reliability of domestic machine tools, the difficulty of reliability implementation method, and the high requirements on the mathematical foundation of technicians, based on long-term technical research and enterprise application on the reliability of electromechanical products, from the perspective of product life cycle, eight laws of reliability in the implementation of machine tools manufacturing enterprises are systematically summarized and refined, including the training law and ability law of enterprise management, the design law and analysis law of product design, the manufacturing law and experiment law of product manufacturing, the operational control law and maintenance law of machine tool operation, the basic concepts of the eight laws are expounded, and the matters needing attention in implementing the eight laws are given. Combining the eight laws with other reliability theory, having important meaning to improve the reliability of the domestic machine tools.