Abstract: The working profile of the arc-face indexing cam is a complex space that cannot be developed. It is difficult to measure and evaluate with conventional methods. In this paper, we put forward a rapid measurement method of cambered cam profile based on characteristic lines by analyzing the characteristics of the cambered cam profile and combining the features of the equidistant curved surface. The measurement system is formed by a coordinate measuring machine(CMM) with a precision turntable, which measures the characteristic lines of the working profile of the arc cam, which improves the measurement speed, directly evaluates the profile error of the cam isometric model, and avoids the probe radius compensation. The feasibility of the measurement method was verified through experiments, and the experimental results were analyzed and processed, and the actual requirements were met. The research content provides theoretical basis and key technology for realizing the integration of globular cam design, processing and measurement.