Abstract: Taking the difficult-to-machine material TA15 titanium alloy as the research object, the orthogonal experiment design method is used to study the influence of the chip breaker size, the machine spindle speed and the feed rate on the chip shape during the drilling process. Experiments show that the size of the chip breaker of the drill is the main factor that affects the chip shape, and the spindle speed and feed of the machine tool are secondary factors; the optimized process parameters select the chip breaker arc radius to be 0.8 mm, and the spindle speed to be 255 r/min, when the feed rate is 0.45 mm/r, the cutting process is stable and chip removal is smooth.