Abstract: Grinding force has important influence on grinding temperature and grinding wheel wear, and is a key index to evaluate TC4 titanium alloy grinding performance. Due to the size and shape differences and randomness of distribution of grains of wheel, it is difficult to describe the grinding process quantitatively. The derivation of existing grinding force models is based on certain assumptions, which is deviated from the practice. Therefore, the derivation of existing grinding force models is based on certain assumptions, which is deviated from the practice. In this paper, a single abrasive grinding force model is established based on the relationship between chip deformation force and the cross-sectional area of the abrasive and the relationship between normal pressure and the pressing depth. Based on the cross-sectional area of the chip and the volume removal rate of the workpiece, the relation between the grinding force of single grain and the grinding force of unit width was established and then the grinding force model of TC4 titanium alloy was deduced. Combined with the experimental data, the analytical formula of grinding force under the experimental conditions was obtained. The analysis shows that the average relative error of normal grinding force is 4.9%, and that of tangential grinding force is 5.1%.