Abstract: With the development of intelligent manufacturing in discrete manufacturing, flexible, precise and modular clamping technology is particularly important in the process of automated processing. In order to realize the automation and intelligent precision machining of multi-variety, small batch, and variable state mixed line production, this paper describes the use scenarios of zero point positioning technology under the discrete intelligent manufacturing model, and focuses on the principle, mathematical model, error analysis, pallet design principle, clamping characteristics, force analysis, and off-machine pre-adjustment tolerance range from the principles of zero point and cone self-centering zero point and cone self-centering technology on one side. It lays a technical foundation for the key technology of clamping in precision automatic processing under discrete intelligent manufacturing mode, and has certain guiding significance for the promotion of discrete intelligent manufacturing.