Abstract: The work aim to study the influence of ultrasonic vibration on milling force and surface integrity of nickel base superalloy. According to the ultrasonic vibration characteristics, the ultrasonic vibration assisted milling force model is established and the key models of finite element analysis are introduced theoretically.In order to study the relationship between milling force and ultrasonic vibration amplitude and frequency, and single factor and multi factor orthogonal simulation cutting experiment are designed. The results show that when the ultrasonic vibration is applied to the milling cutter, the milling force decreases to a certain extent, and within a certain range, the ultrasonic current increases and the milling force decreases. In ordinary milling, the surface topography of the plough has clear scratch boundary, sharp surface protrusion and deep groove marks, and the adjacent cutting marks do not interfere with each other. After ultrasonic vibration, the surface morphology is more round and the transition of adjacent cutting marks is smooth.