Abstract: The copper electroplating cathode titanium plate, being an essential constituent of the copper electroplating process, and its surface quality significantly impacts the electrolytic efficiency, quality, and lifespan of the titanium plates themselves. In response to this question, a simple, efficient, and environmentally friendly surface treatment for the titanium plate is employed, utilizing ultrasonic synergistic cleaning technology with a silicon carbide suspension. The optimal cleaning parameters were investigated through an aluminum foil corrosion method, and an analysis of the synergistic effects during the cleaning process and their underlying mechanisms was conducted. Surface cleanliness, micro-morphology and wettability of titanium plates were characterized and evaluated by SEM+EDS and contact angle measurement. The results showed that the best cleaning effect was achieved at a distance of 78 mm from the transducer, a silicon carbide particle mass fraction of 0.05%, a particle size of 70 nm, a neutral pH, and a temperature of 55°C. The synergistic effect of silicon carbide suspension as a cleaning medium can significantly increase the cleaning efficiency and improve the surface quality of titanium plates. Comparison before and after cleaning shows that synergistic cleaning can effectively remove the contaminants on the surface of titanium plate, improve the surface cleanliness and wettability, and restore the surface micro-morphology and metallic luster of titanium plate. The study provides a reference basis for optimizing the cleaning process of titanium plate.