Abstract: Aiming at the problems of adhesion and “bite” that are prone to occur in titanium alloy fasteners, this study investigates the friction and wear characteristics of four surface state samples under different testing conditions: untreated TC4 surface (LT), pulse anodizing (PA), pulse anodizing+aluminum coating (PA-Al), pulse anodizing+MoS₂ coating (PA-MoS₂), and reveals the influence of different surface state conditions on the friction and wear mechanism. Using a friction and wear testing machine (UMT-3), a ball disc friction and wear experiment was conducted, and the wear morphology of the sample was characterized using SEM-EDS, three-dimensional white light interferometry, optical microscopy instruments, etc. By analyzing and studying the friction coefficient, wear rate, and wear morphology, this study explores the friction characteristics and wear mechanism of titanium alloy friction pairs under different surface states. The results show that the direct contact between TC4 and TC4 materials can effectively prevent adhesive wear. Pulse anodizing (PA) samples have the best friction and wear resistance, followed by anodized MoS₂ coated samples.