Abstract: In order to meet the requirements of surface quality of workpieces, it is necessary to perform milling on TC4 titanium alloy manufactured by selective laser melting, in order to achieve higher precision machining requirements. A simulation model for milling SLM (selective laser melting) TC4 titanium alloy was established to study the effect of cutting parameters on the milling force of milling selective laser melting of titanium alloy. In addition, milling experiments were conducted using the same cutting parameters as the simulation model, and a range analysis was conducted on the simulation and experimental results. The research results indicate that the axial cutting depth a_p has the greatest impact on milling force, followed by cutting speed v_c, and the feed rate per tooth f_z. The optimal milling parameters are: milling speed v_c=55 m/min, feed rate per tooth f_z=0.04 mm/z, and axial cutting depth a_p=0.3 mm.The comparative analysis of errors between milling simulation and experiments shows that the established milling simulation model is reasonable and feasible, so based on this milling simulation model, single factor experimental method was used for simulation and milling experiments. The research results showed that as the cutting speed, axial cutting depth, and feed rate per tooth increased, the milling force increased. However, when the milling speed exceeded 75 m/min, the milling force actually decreased.