Abstract: TB8 titanium alloy is an ultra-high strength and metastable material β Titanium alloys are widely used in the aerospace industry due to their excellent oxidation resistance, corrosion resistance, and comprehensive mechanical properties. To study the hot forging process of TB8 titanium alloy twelve corner bolts for a certain type of machine, isothermal compression experiments were conducted on TB8 titanium alloy specimens at different temperatures and strain rates using the Gleeble-1500D thermal simulation testing machine. The true stress-strain curves under different deformation conditions were obtained and their hot deformation behavior was analyzed. Secondly, the experimental data was imported into the Deform-3D finite element simulation software to perform finite element simulation on the hot heading process of TB8 titanium alloy twelve-angle bolts. An orthogonal experimental optimization scheme was established for the key process parameters of hot heading forming. Through optimization, the TB8 titanium alloy hot heading forming process parameters were obtained. The optimized forming process was analyzed, including equivalent stress field distribution, damage value distribution, and mold stress distribution. Finally, based on the optimized hot heading process parameters and combined with actual production equipment, corresponding molds were designed and hot heading process experiments were conducted. The experimental results showed that the numerical simulation results were basically consistent with the actual production results. The TB8 titanium alloy twelve-angle bolt obtained from the experiment did not show any defects after subsequent mechanical processing, indicating that the hot heading process proposed in this article is feasible, This has certain guiding significance for the actual production of TB8 titanium alloy twelve-point bolts and other similar parts.