Abstract: In order to study the hole exit quality of carbon fiber reinforced polymers (CFRP) laminates drilled with ultrasonic assistance, the ultrasound-assisted hole making experiments of CFRP laminates are carried out by using electroplated diamond nesting drills. By analyzing the raw data of thrust force collected by the Kistler force meter and observing the surface machining quality of hole exit under HIROX RH-2000 3D video microscope, the relationship between process parameters and peak thrust force and critical thrust force are discussed, and the influence law of process parameters on hole exit quality is investigated. The results show that the peak thrust force is inversely proportional to the rotational speed and directly proportional to the feed speed, and the trend of critical thrust force and peak thrust force is basically the same. Delamination damage occurs at the exit of the hole of CFRP laminate, which is manifested as burr and tear defects, and the higher the rotational speed of the spindle, the fewer the defects at the exit, and the higher the feed speed, the more the defects at the exit. The results of the study can be used as a reference for the selection of high-efficiency and high-quality hole making process for CFRP laminates.