Abstract: For the technological innovation system of high-end manufacturing mode transformation, firstly, by comparing and analyzing the recent development trends of the traditional automotive industry and the machine tool industry, the reasons for the rapid development of the automotive industry were revealed, and the problems existing in the development of the machine tool industry and the significance and role of innovative product research and development (R&D) were pointed out. Secondly, four innovative product development models were systematically proposed, namely mapping based development model, analytical development model, reverse development model, and forward development model, with a focus on elaborating on the operational processes and key links of reverse development model and forward development model. Thirdly, taking the positive research and development of Toyota's Lexus brand as an example, the specific implementation path of its high-end product research and development is analyzed. Finally, a comparison was made between the main characteristics of the high-end product development model and the traditional product development model. This provides important reference for building an innovative research and development system for high-end products.