Abstract: Aiming at the difficult machining problem of a certain type of space disk parts made of TC11 titanium alloy, ABAQUS simulation software was used. Based on the actual cutting parameters, the cutting force, heat distribution law and the interaction of cutting parameters during the turning process were analyzed. First, a single factor experiment was used to explore the law of cutting force and heat distribution. Secondly, the orthogonal experiment method is used to study the cutting force and heat distribution law under the interaction, and to fit the multiple linear regression model of the cutting force and heat. Finally, the regression model is optimized with two goals. The experimental results show that the order of the effect of cutting amount on cutting force is: depth of cut>feed>cutting speed, and the order of influence on cutting temperature is feed>cutting speed>depth of cut. The regression model is highly fitting test, and the algorithm optimization can effectively optimize the cutting parameters and reduce the cutting force and cutting heat.