Abstract: In the development of non-standard automation equipment, it is difficult to carry out accurate reliability analysis due to the lack of previous fault data. In order to solve the above problems, this paper first improves the traditional FMECA method, gives dynamic weights to different experts by depended uncertain ordered weighted averaging, and determines the relative weights between different evaluation indexes by analytic hierarchy process. Secondly, according to the improved FMECA method, the reliability of the washing machine drum assembly line newly developed by a household appliance enterprise is analyzed. Finally, the analysis results before and after the improvement are compared. The results obtained by the improved FMECA method are generally consistent with those before the improvement, but greatly reduce the impact of the occasional judgment errors of experts on the analysis results, and consider the relative weight between the evaluation indexes to improve the accuracy of the analysis results.